ncRNA name | bcl-2 shRNA |
ncRNA Category | shRNA |
Disease name | cataract |
Species | Homo sapiens |
Tissues/Cell_line | human lens epithelial cells (HLECs) |
Methods | shRNA knockdown, Western blot, qPCR, Annexin V-PI staining |
Expression pattern | associated |
Functional description | Two pairs of oligonucleotides were synthesized and inserted into plasmid PGCsi to generate shRNA eukaryotic expression vectors, named P1 and P2. P1 and P2 can both down-regulate the expression of bcl-2, and induce the apoptosis of HLEC. |
PubMed ID | 19957693 |
Year | 2009 |
Title | Inhibition of bcl-2 by shRNA to induce apoptosis in human lens epithelial cells. |
Drug-related ncRNA | NA |
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